EXTRACELLULAR VESICLES DERIVED FROM PPRV-INFECTED CELLS ENHANCE SIGNALING LYMPHOCYTE ACTIVATION MOLECULAR (SLAM) RECEPTOR EXPRESSION AND FACILITATE VIRUS INFECTION.

Extracellular vesicles derived from PPRV-infected cells enhance signaling lymphocyte activation molecular (SLAM) receptor expression and facilitate virus infection.

Peste des petits ruminants virus (PPRV) is an important pathogen that seriously influences the productivity of small ruminants worldwide.PPRV is lymphotropic in nature and SLAM was identified as the primary receptor for PPRV and other Morbilliviruses.Many viruses have been demonstrated to engage extracellular vesicles (EVs) to facilitate their repl

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Deep Learning for Prediction of Progression and Recurrence in Nonfunctioning Pituitary Macroadenomas: Combination of Clinical and MRI Features

ObjectivesA subset of non-functioning pituitary macroadenomas (NFMAs) may exhibit early progression/recurrence (P/R) after tumor resection.The purpose of this study was to apply deep learning (DL) algorithms for prediction of P/R in NFMAs.MethodsFrom June 2009 to December 2019, Pu 78 patients diagnosed with pathologically confirmed NFMAs, and who h

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The uncertainty, challenges, and variability in tuberculosis congregate setting investigations: The concentric circle model revisited

In the United States MAG PWD ORANGE tuberculosis programs routinely conduct congregate setting contact investigations in locations such as schools, workplaces, social/recreational sites, nursing homes and prisons.Both documented and anecdotal reports describing these investigations have indicated, in many cases, the unnecessary testing of large num

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